In Vitro Fertilization (IVF) is becoming a more popular option for couples having difficulty in naturally conceiving a child. There are many clinics and doctors that specialize in this field. The procedure is a work in progress as IVF has been continually improved to increase the chances of pregnancy and reduce the possibility of risks and complications.
As with other treatments, not all attempts are successful and some result to failed IVF. The reported success rate or those that resulted in live birth is around 35% for women above the age of 32. For women who had failed IVF, it is frustrating and some would stop with the treatment. The IVF is also very expensive and pregnancy is not guaranteed.
Some, however, still opt to have second IVF after the first failed IVF. Others look for other ways to get pregnant or turn to adoption instead. Doctors have been working to find out the reasons why certain pregnancies do not push through to help couples everywhere.
Causes of Failed IVF
It is believed that the success and failure of the IVF procedure rely on many factors. The most considered factor is the physical condition of the recipient as age and reproductive health play important roles in having a successful IVF. The older the woman gets the lesser her chances of getting pregnant. Reproductive organ issues such as endometriosis, low uterus and poor ovarian response significantly affect the success rate because these conditions would hinder the embryo from implanting properly to the uterus causing arrest.
Other factors are the number and quality of the gametes used, genetic make-up of the embryo and the cause of infertility. The quality of the gametes used in the procedure can have a big impact on the success of the IVF treatment. There are some couples who may have defective chromosomes that prevent embryos from properly developing. In these cases, donors are employed. Donor IVF has a success rate of up to 50%. Of course, this would need consent from both parties.
Failed IVF could also be due to incompetence during egg aspiration and transfer. In some cases, there is trauma during the egg retrieval and embryo transfer. This could be because the cervix is not wide enough to accommodate the catheter to facilitate smooth exchange. Doctors have been looking for better techniques however there are more complications to consider.
Another study also shows that failed IVF is caused by the over active immune response of the female. The woman's body treats the transferred embryo as a threat and eliminates the problem. To suppress the immune system, transfusion of blood that contains antibodies is required to allow the embryo to implant without any problem.
What's Next after Failed IVF?
Some clinics include stress management to improve the rate of IVF. It is also essential to have a healthy lifestyle that includes healthy diet and exercise. Smoking and excessive caffeine and alcohol intake should be avoided.
The first and second IVF still have the same success and fail rate and they follow the same factors and criteria. The woman or couple should discuss with the doctor about the causes of the failed IVF and the probability of failing again. If the specific cause of the failure is found, it would be easier to determine what the next steps should be.